Prompt Cast
The Origins and Impact of HIV/AIDS
TLDR HIV-1, the virus responsible for the global pandemic of HIV/AIDS, is believed to have originated from a type of chimpanzee in West Africa and was transmitted to humans through ingesting infected blood. HIV/AIDS is still a major problem worldwide, with millions infected and dead, but advancements in treatment have allowed people to live longer with the disease.
Timestamped Summary
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HIV-1, the virus responsible for the global pandemic of HIV/AIDS, is believed to have originated from a type of chimpanzee in West Africa and was transmitted to humans, although the exact method of transmission is still unknown.
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HIV is believed to have originated from a type of chimpanzee in West Africa and was transmitted to humans through ingesting infected blood, and in the late 70s and early 80s, healthy people in Los Angeles and New York started getting sick, leading to the term AIDS being used.
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HIV/AIDS is still a very big problem, with 78 million people worldwide infected and 39 million people dead, and Sub-Saharan South Africa being the most threatening region with one in 20 people having HIV.
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HIV/AIDS is a progressive disease that goes through stages, with AIDS being the end stage of HIV infection.
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HIV/AIDS used to be a death sentence, but with advancements in treatment, people can now live for decades with the disease, although the designation of having AIDS remains for life unless cured.
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HIV can be transmitted through sexual contact, sharing needles, breastfeeding, mother to baby during pregnancy or birth, and blood transfusions, although the risk of transmission through blood transfusions has significantly decreased since the 1980s.
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Mosquitoes cannot transmit HIV because the virus does not replicate within the mosquito and the virus is not present in the mosquito's saliva.
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HIV attaches to T helper cells, hijacks them, and turns them into HIV factories through a seven-part process of invasion and replication.
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HIV hijacks cells to build new HIV virions instead of performing their normal functions, and when the infected cell self-destructs, it signals other cells to surround it and self-destruct as well, making HIV an insidious and destructive disease.
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HIV forms reservoirs in the body that can hide and become active at any time, making it difficult to eradicate the virus and leading to the progression of AIDS.
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MSM (men who have sex with men) represent about 4% of the male population in the United States, but accounted for 78% of new HIV infections and 54% of all people living with HIV in the United States in 2010.
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