Women's Sexual Health: Understanding Physiology, Hormones, and Treatment Options

TLDR This podcast episode delves into the complexities of women's sexual health, covering topics such as hormonal influences, postpartum changes, emerging testing methods, and treatment options like testosterone replacement therapy and vaginal DHEA. It emphasizes the importance of comprehensive care that considers psychological, biological, and relational factors to address sexual health concerns effectively.

Timestamped Summary

00:00 The episode focuses on women's sexual health, covering female physiology, potential problems, treatments, and case studies to differentiate between desire and arousal.
08:27 Hormones play a significant role in women's sexual response throughout different life stages, with menopause being a defining moment due to changes in estrogen levels affecting vaginal comfort and declining androgens impacting desire.
16:22 The rising rate of cesarean sections in the United States and the misconception that it's better for sexual health leads to a lack of awareness about postpartum hormonal changes affecting sexual function, particularly for breastfeeding women.
24:09 Clitoral Doppler testing and coronary calcium scores are emerging areas in understanding women's sexual health and overall well-being, highlighting the need for more comprehensive approaches beyond simplistic solutions like lubricants.
31:43 Understanding women's sexual health involves assessing various factors such as psychological distress, relationship dynamics, cultural influences, and biological aspects to provide comprehensive care and support.
39:45 The sexual response cycle for women involves desire, arousal, and satisfaction, with the importance of separating these components for effective evaluation and treatment.
47:15 The importance of evaluating sexual desire, arousal, and satisfaction in women to understand and address sexual health concerns effectively.
55:03 The impact of hormonal contraception on sexual function in women, including potential issues related to estrogen levels, pain, mood, and testosterone levels.
01:02:37 Changes in SHBG levels and free testosterone due to long-term use of birth control pills can impact women's sexual desire and may require further investigation and potential treatment with exogenous testosterone.
01:10:41 Testosterone replacement therapy for women, specifically through transdermal patches, has shown positive effects on sexual function and desire, but faces challenges in gaining FDA approval due to lack of long-term safety data and historical biases.
01:18:56 Prescribing testosterone for women is challenging due to lack of FDA-approved products, leading to the need for imprecise methods like cutting patches or using compounded creams or injections.
01:26:52 Prescribing testosterone for women is not the solution for hormonal imbalances in premenopausal women, and switching contraception methods may be a more appropriate intervention.
01:34:20 Vaginal DHEA, such as intrarosa, is a viable option for treating vulvovaginal atrophy and dyspareunia in menopausal women due to its efficacy and safety with minimal systemic absorption.
01:42:25 The process of achieving orgasm in women involves a complex interplay of pelvic floor muscles, blood vessel dilation, nerve stimulation, neurotransmitter release, and local hormone activity, leading to a range of sensations and experiences that vary among individuals.
01:50:14 Women's orgasmic response is usually maintained unless organic or psychological factors intervene, and a quick workup involves assessing sexual function, knowledge of self-stimulation, partner communication, and potential need for increased stimulation with age.
01:57:45 Office counseling involves assessing lifestyle factors, relationship dynamics, and potential modifiable medication factors before considering pharmaceutical interventions for low sexual desire in women.
02:05:27 A self-injected drug for women to enhance sexual desire and arousal on demand has shown promising results with manageable side effects and cost considerations.
02:13:12 Prescription drugs for sexual health in women may be underutilized due to lack of awareness and understanding of available treatment options.
02:21:14 Hormone therapy, specifically combined estrogen progesterone therapy, is a highly effective treatment for menopausal symptoms with minimal risk of adverse effects.
02:29:10 Using an IUD for endometrial protection can be a strategy for managing menopausal symptoms with potential benefits for bone health as well.
02:37:01 Ospemifene is an FDA-approved oral serum indicated for vulva vaginal atrophy causing dyspareunia, potentially useful for breast protection and bone health, although not commonly prescribed.
Categories: Health & Fitness

Women's Sexual Health: Understanding Physiology, Hormones, and Treatment Options

Women's sexual health: Why it matters, what can go wrong, and how to fix it | Sharon Parish, M.D.
by The Peter Attia Drive

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