The Science of Gratitude and its Impact on Health and Well-being

TLDR Regular gratitude practices, such as storytelling and receiving gratitude, can activate neural circuits associated with pro-social behaviors and enhance physical and mental health. These practices have been shown to have a pervasive and long-lasting impact on subjective well-being, resilience to trauma, social relationships, and overall health.

Timestamped Summary

00:00 The science of gratitude and effective gratitude practices can positively impact a wide range of health variables, including cardiovascular health, relationships, mental health, and physical and cognitive performance.
05:27 Regular gratitude practices have been shown to have a pervasive and long-lasting impact on subjective well-being, resilience to trauma, social relationships, and mental and physical health.
10:52 Gratitude falls under the category of pro-social behaviors, which are designed to bring us closer to different types of things and enhance the level of detail that we extract from those experiences, and it can help balance out the defensive circuits in our brain that are associated with fear and backing up.
16:52 Gratitude practices, when performed regularly, can shift neural circuits associated with pro-social behaviors and enhance physical and mental health.
22:44 Gratitude practices that involve simply listing things you are grateful for are not particularly effective in shifting neural circuitry and enhancing activation of the prefrontal cortex and pro-social neural networks.
28:48 Receiving gratitude is more effective in shifting neural circuitry and enhancing activation of the prefrontal cortex and pro-social neural networks than giving gratitude.
34:44 Watching narratives about other people experiencing positive things in their lives, particularly stories of survivors of genocide receiving help and expressing gratitude, activates neural circuits associated with pro-social behaviors and gratitude in the brain.
40:46 To activate gratitude circuits in the brain, it is important to either put yourself in the mindset of another person or directly receive gratitude, and one effective way to do this is through storytelling.
47:04 Gratitude practices, such as storytelling, can lead to neuroplasticity in the brain and activate neural circuits associated with gratitude, resulting in positive effects on physiology and a more relaxed state.
52:40 Repeated gratitude practice can change the way brain circuits work and the way the brain and heart interact, leading to changes in resting state functional connectivity in emotion and motivation related brain regions.
58:35 Regular gratitude practice can shift the functional connectivity of emotion pathways, reducing anxiety and fear circuits while enhancing positive emotion and motivation circuits, and can be as brief as one minute or five minutes, three times a week, with the best time to practice being in the morning or before bed.
01:04:17 Regular gratitude practice has been shown to reduce amygdala activity and the production of inflammatory cytokines, such as TNF alpha and IL6, leading to potential improvements in emotional well-being and overall health.
01:10:17 Enhancing serotonin levels through the use of supplements like 5-HTP or tryptophan, or the herb Kana, combined with a gratitude practice, may potentially amplify the effects of gratitude on neural plasticity and overall well-being.
01:16:11 A gratitude practice should be grounded in a narrative or story, which can involve either receiving or observing genuine thanks, and should be accompanied by simple bullet points that serve as reminders of the story, followed by reading the bullet points as a cue to the nervous system and spending a few minutes feeling into the genuine experience of gratitude, ideally done three times a week at any time of day.

The Science of Gratitude and its Impact on Health and Well-being

The Science of Gratitude & How to Build a Gratitude Practice
by Huberman Lab

Browse more Science