Prompt Cast
The Purpose and Function of the Appendix in the Human Body
TLDR Recent research has shown that the appendix serves a purpose in the human body, specifically in relation to the microbiome and the digestive system. It acts as a safe house for good bacteria, produces immune cells, and plays a role in preventing overactive immune responses.
Timestamped Summary
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05:02
The appendix is a small worm-like organ that hangs off the bottom of the large intestine and was previously thought to be vestigial, but recent research has shown that it has a purpose in the human body.
09:40
The large intestine contains a microbiome that plays a crucial role in digesting food and breaking it down so that it can be absorbed, and the appendix was previously believed to be a vestigial organ with no function.
14:20
The appendix serves a function in the body, specifically in relation to the microbiome and the digestive system.
19:03
The appendix serves as a safe house for good bacteria and also produces immune cells, but it is still possible to live without it.
23:43
The hygiene hypothesis suggests that because our immune systems are not exposed to certain pathogens, they can become overactive and attack not only allergens like peanuts, but also the appendix, leading to inflammation and appendicitis.
28:14
The hygiene hypothesis explains why appendicitis is more common in developed countries, while the safe house theory suggests that the appendix does have a purpose and role.
33:13
Appendicitis occurs when the narrow opening of the appendix gets clogged with bacteria, certain seeds, or fecaliths, leading to inflammation, pain, fever, and nausea, and if left untreated, it can result in a ruptured appendix and a potentially life-threatening infection.
37:47
The appendix serves a function in young people as part of the immune system, but as you get older, it stops functioning and can become problematic, leading to appendicitis.
42:20
Houdini's death was likely caused by a punch to his already inflamed appendix, although it is unclear whether he already had appendicitis or not.
46:39
A 10-year-old listener named Jack from High Watha, Iowa suggested doing a podcast episode on child labor, which the hosts thought was a great idea.
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