00:00 Lewis and Clark were explorers who embarked on the Corps of Discovery expedition, which was the brainchild of Thomas Jefferson and was a result of the Louisiana Purchase.

05:16 Lewis and Clark were sent by Thomas Jefferson to explore the newly acquired Louisiana Purchase and inform the Native Americans that they were now living in America.

09:54 Lewis and Clark formed a co-captain partnership and ran the expedition like a democracy, with minimal problems and a strong sense of camaraderie.

14:33 Lewis and Clark encountered the Titansu or Lakota Indians, who were known as the "pirates of the Missouri," and had a standoff with them over a canoe, but were able to pass through unscathed.

19:02 Sacagawea was a crucial member of the expedition as a translator and a symbol of peace, and she also played a key role in retrieving important records when a boat overturned.

24:00 Lewis and Clark encountered various new animals and crossed the continental divide, but faced challenges such as disagreements and a difficult portage around the Great Falls of Montana.

28:28 Lewis and Clark meet the Shoshone, who were in bad shape, and eventually find Sacagawea, who recognizes one of the women as her childhood friend and reunites with her tribe, before proceeding across the continental divide with the help of a tour guide named Old Toby and encountering difficulties with horse meat and illness from the food, but eventually reaching the Columbia River and leaving their horses with the Nes Perce tribe before finally reaching the Pacific Ocean.

33:16 Lewis and Clark camped on the Pacific for four months, waiting for a boat that they didn't actually plan on taking back, and then put it to a vote to decide how to return home.

37:51 Lewis and Clark retraced their trail back home, had some violent encounters with the Blackfeet Indians, and eventually reunited with the rest of the expedition before arriving in St. Louis to a cheering crowd.

42:37 York, who did not receive any land or money, had a difficult reentry into slavery and asked Clark for his freedom, but Clark refused and even wrote a letter to his brother saying that York was being uppity and had to be beaten, although there are disputed accounts of whether York was eventually freed or escaped.

47:20 Lewis and Clark believed in living in harmony with Native Americans, but America did not learn the lessons they brought back and instead followed the idea of manifest destiny.