00:00 Marijuana has a long history of being cultivated for industrial and medicinal purposes, with records of its use dating back thousands of years.

05:54 There are different types of cannabis plants, including cannabis indica and cannabis sativa, and there is ongoing debate among botanists about whether they are different varieties of the same plant or different species.

11:39 In the 1930s, there was a fear surrounding marijuana due to newspaper reports of violent crimes committed by people under the influence of the drug, leading to the criminalization of marijuana with the passing of the Marijuana Tax Act in 1937.

17:02 Mandatory minimum sentences were reenacted in 1986, resulting in the same jail time for possessing 100 marijuana plants as possessing 100 grams of heroin.

22:42 Marijuana plants are easily wind-borne and spread through pollinization, and female plants need to be separated from male plants to prevent unwanted pollination; there are hundreds of chemicals in the marijuana plant, with THC being the main psychoactive ingredient stored in the trichomes of the plant; THC levels have been increasing over time, leading to stronger effects on users; when smoked, THC is carried into the lungs and then into the bloodstream, reaching the brain within seconds and causing various physiological effects.

28:22 The endocannabinoid system in the brain is responsible for regulating neurotransmitters and maintaining homeostasis, but when THC from marijuana binds to the endocannabinoid receptors, it hijacks the system and can cause symptoms like impaired learning and coordination.

33:44 THC hijacks the endocannabinoid receptors in the brain, causing symptoms like paranoia and anxiety, as well as stimulating appetite and causing a release of dopamine.

39:14 When marijuana is ingested orally, it is metabolized in the liver into another psychoactive chemical that is not present when it is smoked, resulting in longer-lasting effects and a delayed onset.

44:26 Marijuana has been found to have various medicinal benefits, including reducing muscle spasms in multiple sclerosis patients, fighting and destroying cancer cells, alleviating pain and inflammation, and potentially being reclassified away from a schedule one substance.

49:46 The potency of marijuana has increased significantly over the years, with the average amount of THC rising from 3.4% to 8.8% between 1993 and 2008, according to the University of Mississippi Potency Monitoring Project.

55:11 The potency of marijuana has increased significantly over the years, with the average amount of THC rising from 3.4% to 8.8% between 1993 and 2008, and now up to 25% in some cases.

01:00:37 A long-term study found that low to moderate use of marijuana is less harmful to the lungs than exposure to tobacco.